Figure 10.

Rank fitness landscapes of four peptides in each of two patients. Each peptide is denoted by amino acids subscripted with their loci. A directed edge i → j exists between peptides i and j if the posterior fitness difference F_j − F_i can credibly be inferred to be >0, i.e., if, given the model, there is evidence for peptide j being fitter than peptide i. Vertices with dark shading possess larger than average and open vertices possess lower than average fitness φ = 1.