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PPARγ ligands inhibit Th17 cells differentiation. (A) Naïve CD4+ T cells were purified and differentiated into Th17 cells with or without 25 μM of ciglitazone, rosiglitazone, and troglitazone. After 7 days, IL-17 producing CD4+ cells were analyzed using FACS. (B) Data from IL-17-producing cells with various concentrations of PPARγ ligand are indicated. One-way ANOVA was used for statistical analysis (p<0.01).
