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. Author manuscript; available in PMC: 2015 Jan 8.
Published in final edited form as: Cardiovasc Toxicol. 2005;5(1):29–41. doi: 10.1385/ct:5:1:029

Fig. 6.

Fig. 6

AsIII exposure in drinking water leads to increased plasminogen activator inhibitor-1 (PAI-1) in plasma. Circulating PAI-1 protein levels were determined in the plasma of mice after 20 wk of exposure to normal or AsIII-containing drinking water. During necropsy, blood was collected by cardiac puncture into sodium citrate and spun at 2500g for 10 min at 4°C and platelet-poor plasma collected and stored at −80°C until assay for total PAI-1 by enzyme-linked immunosorbent assay. Each bar represents the mean ± SD PAI-1 level from five mice. Significance is designated by **p < 0.01.