Skip to main content
. Author manuscript; available in PMC: 2016 Feb 15.
Published in final edited form as: Behav Brain Res. 2014 Nov 29;279:202–210. doi: 10.1016/j.bbr.2014.11.037

Fig. 1.

Fig. 1

Reduction of D1R binding activities in the striatal membrane fractions and brain slices of Dyt1 ΔGAG heterozygous KI mice. (A) Scatchard plot of D1R binding activity in the striatal membrane fractions shows that Dyt1 ΔGAG heterozygous KI mice had reduced binding of D1R antagonist [3H] SCH-23390. (B) Dyt1 ΔGAG heterozygous KI mice had an over 30% reduction in D1R binding. (C) Representative autoradiographs with D1R radioligand [3H] SCH-23390 in WT and Dyt1 ΔGAG heterozygous KI mice. (D) Radioligand autoradiographs confirmed the reduction of D1R in Dyt1 ΔGAG heterozygous KI mice. Vertical bars represent means ± standard errors. *p < 0.05.