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. 2014 Aug 1;23(10):1369–1379. doi: 10.1002/pro.2521

Figure 6.

Figure 6

Cross-propagation of DSOs with Aβ42 monomer. (A) ThT aggregation reactions of 15 μM Aβ42 alone (▪) or co-incubated with 1 μM DSO4–13 (○), DSO3–10 (▴),DSO3–6 (▿), DSO2–5 (⋄), or DSO2–3 (◃) (n = 3). (B) Western blot of the reactions in (A) after 72 h aliquots probed by Aβ-specific monoclonal antibody Ab5 [indicated with an arrow in (A)]: Control Aβ42 (lane C), with DSO4–13, DSO3–10, DSO3–6, DSO2–5, and DSO2–3 (lanes 1–5), respectively. (C) CD spectra of cross-propagation reactions at 72 h. (D) Plots of difference in molar ellipticities at 216 and 200 nm obtained from (C).