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. Author manuscript; available in PMC: 2015 Nov 24.
Published in final edited form as: Chembiochem. 2014 Oct 7;15(17):2556–2562. doi: 10.1002/cbic.201402286

Table 1.

Styrene cyclopropanation catalyzed by hemin and proteins spiked with hemin. 10 μM of hemin or equimolar concentrations of hemin and protein were mixed and incubated under anaerobic conditions at 24°C for 1h in 5% EtOH co-solvent, 20 mM styrene, 10 mM EDA under reducing conditions.

Catalyst: yield % TTN cis/trans %cisee % transee
Hemin 18 175 14:86 rac rac
BSA - - - - -
BSA + hemin 35 349 9:91 7 -10
HSA - - - - -
HSA + hemin 57 567 9:91 15 17
Lysozyme - - - - -
Lysozyme + hemin 8 78 13:87 rac rac

The data represent triplicates with standard errors within the range of 20%. - denotes no product formation; rac indicates enantioselectivity below 5% ee.