Table 1.
Patient Characteristics
| Characteristics (n = 111) | N |
|---|---|
| Sex | |
| Male | 52 (47%) |
| Female | 59 (53%) |
| Median age in years (range) | 62 (22–87) |
| Tumor type | |
| Lung cancer | 91 (82%) |
| Breast cancer | 13 (12%) |
| Lymphoma | 3 (3%) |
| Others* | 4 (3%) |
| Smoking history | 92 (83%) |
| Median pack years (range) | 40 (0–150) |
| Location of tumor (lung cancer) | |
| Central | 59 (53%) |
| Peripheral | 32 (29%) |
| COPD | 23 (21%) |
| Thoracic surgery prior to RT | 33 (30%) |
| Chemotherapy† | 55 (50%) |
| Mean lung dose (Gy) | 16.8 (4.2–35.5) |
| Symptomatic radiation pneumonitis§ | |
| Grade 0–1 | 84 (76%) |
| Grade 2–3 | 27 (24%) |
*
Kidney, melanoma, esophagus, thymus.
§
A modified version of the Common Toxicity Criteria of the National Cancer Institute was used 20, 30.
†
Most are platinum-based regimens received by lung cancer patients prior to RT.
Abbreviations: COPD = Chronic obstructive pulmonary disease; RT = radiation therapy.