Table 2.
Correlation between the average increases in lung density and reductions in PFTs for the overall group
| No. of tests | r | p-value | ||
|---|---|---|---|---|
| Overall – all data considered 3 to 24 months post-RT |
CT vs. DLCO | 203 | 0.26 | <0.001 |
| CT vs. FEV1 | 203 | 0.34 | <0.001 | |
| 6-month follow-up interval | CT vs. DLCO | 72 | 0.29 | 0.015 |
| CT vs. FEV1 | 72 | 0.35 | 0.003 | |
| Averaged data over all follow-up intervals | CT vs. DLCO | 111 | 0.23 | 0.016 |
| CT vs. FEV1 | 111 | 0.36 | <0.001 | |
| At the time of maximum PFT decline | CT vs. DLCO | 111 | 0.20 | 0.034 |
| CT vs. FEV1 | 111 | 0.30 | 0.001 | |
| At the time of maximum density increase | CT vs. DLCO | 111 | 0.17 | 0.070 |
| CT vs. FEV1 | 111 | 0.37 | <0.001 |
Abbreviations: DLCO = diffusion capacity for carbon monoxide; FEV1 = forced expiratory volume in 1 second; PFT = pulmonary function tests