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. Author manuscript; available in PMC: 2015 Jan 8.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2008 Dec 10;74(3):781–789. doi: 10.1016/j.ijrobp.2008.08.053

Table 2.

Correlation between the average increases in lung density and reductions in PFTs for the overall group

No. of tests r p-value
Overall – all data considered
3 to 24 months post-RT
CT vs. DLCO 203 0.26 <0.001
CT vs. FEV1 203 0.34 <0.001
6-month follow-up interval CT vs. DLCO 72 0.29 0.015
CT vs. FEV1 72 0.35 0.003
Averaged data over all follow-up intervals CT vs. DLCO 111 0.23 0.016
CT vs. FEV1 111 0.36 <0.001
At the time of maximum PFT decline CT vs. DLCO 111 0.20 0.034
CT vs. FEV1 111 0.30 0.001
At the time of maximum density increase CT vs. DLCO 111 0.17 0.070
CT vs. FEV1 111 0.37 <0.001

Abbreviations: DLCO = diffusion capacity for carbon monoxide; FEV1 = forced expiratory volume in 1 second; PFT = pulmonary function tests