Table I.
Sugar | Derivatization Level (mol sugar/mol Ab) | HMW Level (%) | Endotoxin level (EU/mL) |
---|---|---|---|
Unmodified | – | 2.2 | <0.2 |
IMT-Man | 18.2 | 5.3 | 0.3 |
High Man Glycation | 17.5 | 6.7 | < 0.2 |
Low Man Glycation | 1.4 | 4.6 | < 0.2 |
HMW high molecular weight, EU endotoxin units, IMT 2-imino-2-methoxyethyl 1-thio