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. 2014 Nov 21;17(1):237–244. doi: 10.1208/s12248-014-9694-4

Table I.

Derivitization Levels on mAbA

Sugar Derivatization Level (mol sugar/mol Ab) HMW Level (%) Endotoxin level (EU/mL)
Unmodified 2.2 <0.2
IMT-Man 18.2 5.3 0.3
High Man Glycation 17.5 6.7 < 0.2
Low Man Glycation 1.4 4.6 < 0.2

HMW high molecular weight, EU endotoxin units, IMT 2-imino-2-methoxyethyl 1-thio