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Effect of hesperetin on microvessel outgrowth arising from mouse aortic rings. Aortic rings isolated from mice were embedded in Matrigel in 48-well plates and then fed medium containing various concentrations of hesperetin for 7 days. Representative photographs of three independent experiments are shown. The microvessel length was measured on day 7 of culture. The values are the means±SD (n=3), and *P<0.05, **P<0.01 versus control cells.
