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Replicable risk SNPs (p<0.05) for alcohol dependence in SERINC2 in subjects of European descent
| MAF | European-Americans | Australians | Meta-analysis | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| SNP | Gene | Location | Cases | Controls | OR | p-value | q-value | OR | p-value | Z-score | P-value |
| rs77840364 | SERINC2 | Intron 10 | 0.030 | 0.022 | 1.45 | 0.029 | 0.0433 | 8.00 | 0.020 | 2.348 | 0.0189 |
| rs115360541 | SERINC2 | Intron 12 | 0.065 | 0.043 | 1.50 | 0.008 | 0.0256 | 2.00 | 0.019 | 2.815 | 0.0049 |
