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. Author manuscript; available in PMC: 2015 Jan 8.
Published in final edited form as: J Phys Chem B. 2013 Jan 23;117(5):1219–1224. doi: 10.1021/jp3089462

Figure 1.

Figure 1

Graphical depiction of density matrix evolution (upper graph) with the hyper-SHIELDED sequence (lower graph). Para-hydrogen singlet states (represented by bold circles, middle left) are converted into pure heteronuclear magnetization (bold circle, middle right) for strongly coupled spin systems (I1I2S or AA′X). Circled symbols in the upper diagram represent density matrix terms and correspond directly with numbered equations (see Theory).