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. Author manuscript; available in PMC: 2015 Jan 8.
Published in final edited form as: Cancer Res. 2009 Aug 4;69(16):6414–6422. doi: 10.1158/0008-5472.CAN-09-1223

Fig. 2.

Fig. 2

POX caused G2 cell cycle arrest. (A). POX was dose-dependently repressed by increasing DOX concentrations in DLD-1 Tet-Off POX cells. Cell growth assay showed increasing DOX concentrations released DLD-1 cells from POX-mediated inhibition of growth. (B). Flow cytometry assay showed that increasing POX expression with decreasing DOX concentration induced G2 cell cycle arrest. (C). Western blot showed the induction of Geminin, by increasing POX expression with decreasing DOX. (D). The effects of POX expression with decreasing DOX concentrations on several important regulators of G2 phase determined by Western blots.