Table 2. Univariable relationship between HIV disease status and serostatus for HPV 16 and 18 among HIV-positive men who have sex with men.
| Characteristic (n) | HPV 16+n (%) | HPV 16-n (%) | RR (95% CI)‡ | HPV 16+ Neut. Titer Mean ± SD | HPV 18+n (%) | HPV 18-n (%) | RR (95% CI)‡ | HPV 18+ Neut. Titer Mean ±SD |
|---|---|---|---|---|---|---|---|---|
| Years of HIV positivity¶ | ||||||||
| ≤5 (42) | 22 (52) | 20 (48) | 1.0 Referent | 1723 ±2217 | 25 (60) | 17 (40) | 1.0 Referent | 496 ±683 |
| >5-10 (79) | 34 (43) | 45 (57) | 0.82 (0.56-1.2) | 1087 ±1564 | 36 (46) | 43 (54) | 0.77 (0.54-1.1) | 440 ±609 |
| >10-15 (162) | 68 (42) | 94 (58) | 0.80 (0.57-1.1) | 1059 ±2176 | 74 (46) | 88 (54) | 0.77 (0.57-1.04) | 688 ±860 |
| >15 (6) | 3 (50) | 3 (50) | 0.95 (0.41-2.2) | 467 ±306 | 4 (67) | 2 (33) | 1.1 (0.60-2.1) | 400 ±283 |
| Mean±SD | 9.5±4.2 | 10±3.7 pt-test=0.30† | ptrend=0.34§ | ptrend=0.31ˆ | 9.5±4.2 | 10±3.6 pt-test=0.27† | ptrend=0.29§ | ptrend=0.97ˆ |
| CD4 Levelβ | ||||||||
| >500 (6) | 44 (41) | 63 (59) | 1.0 Referent | 1415 ±2088 | 48 (45) | 59 (55) | 1.0 Referent | 575 ±810 |
| 200-500 (107) | 70 (51) | 67 (49) | 1.2 (0.94-1.6) | 1099 ±2128 | 69 (50) | 68 (50) | 1.1 (0.86-1.5) | 564 ±735 |
| <200 (137) | 14 (30) | 32 (70) | 0.74 (0.45-1.2) | 668 ±541 | 21 (46) | 25 (54) | 1.0 (0.70-1.5) | 681 ±781 |
| Mean±SD | 447±236 | 444±277 pt-test=0.94† | ptrend=0.62§ | ptrend=0.23ˆ | 438±252 | 452±266 pt-test=0.66† | ptrend=0.74§ | ptrend=0.60ˆ |
| HIV viral loadρ | ||||||||
| <500 (154) | 64 (42) | 90 (58) | 1.0 Referent | 1259 ±2295 | 74 (48) | 80 (52) | 1.0 Referent | 405 ±426 |
| 500-4k (52) | 23 (44) | 29 (56) | 1.1 (0.74-1.5) | 900 ±1637 | 24 (46) | 28 (54) | 96 (0.69-1.3) | 1196 ±1273 |
| >4k-20k (47) | 25 (53) | 22 (47) | 1.3 (0.92-1.8) | 1014 ±1573 | 24 (51) | 23 (49) | 1.1 (0.77-1.5) | 548 ±747 |
| >20k (35) | 14 (40) | 21 (60) | 0.96 (0.62-1.5) | 1621 ±2004 | 15 (43) | 20 (57) | 0.89 (0.59-1.4) | 577 ±604 |
| Mean±SD | 14180±52149 | 18764±61689 pt-test=0.50† | ptrend=0.57§ | ptrend=0.53 | 17200±60310 | 16358±55341 pt-test=0.90† | ptrend=0.79§ | ptrend=0.84 |
‡
Confidence intervals for relative risks (RR) were computed using robust error variances.
†
T-test comparing mean values for sero-positive and sero-negative individuals for indicated characteristic.
§
Li kelihood ratio trend test for relative risk.
ˆ
Generalized linear model trend test.
*
Analysis of variance F-test.
¶
n=7 observations had unknown values and were excluded from analyses.
β
n=46 observations had unknown values and were excluded from analyses.
ρ
n=8 observations had unknown values and were excluded from analyses.