. Author manuscript; available in PMC: 2015 Jan 8.

Published in final edited form as: J Acquir Immune Defic Syndr. 2013 Dec 15;64(5):479–487. doi: 10.1097/QAI.0b013e3182a7acd2

Table 5. Multivariable relationship between study characteristics and serostatus for HPV 16 and 18 among HIV-positive men who have sex with men.

Characteristic^¶	HPV 16-seropositive RR (95% CI)^‡	HPV 18-seropositive RR (95% CI)^‡

Age at enrollment (yrs)
≤30	1.0 Referent	1.0 Referent
31-40	1.2 (0.59-2.4)	1.0 (0.47-2.2)
41-50	1.4 (0.68-2.8)	1.3 (0.60-2.8)
51-60	1.6 (0.72-3.5)	1.4 (0.62-3.4)
>60	1.2 (0.44-3.4)	2.0 (0.79-5.1)
	p_trend=0.21^§	p_trend=0.019^§
Years of HIV positivity
≤5	1.0 Referent	1.0 Referent
>5-10	0.75 (0.48-1.1)	0.77 (0.53-1.1)
>10-15	0.74 (0.51-1.1)	0.69 (0.50-0.95)
>15	0.75 (0.36-1.5)	0.89 (0.46-1.7)
	p_trend=0.17^§	p_trend=0.087^§
CD4 Level
>500	1.0 Referent	1.0 Referent
200-500	1.2 (0.91-1.6)	1.2 (0.87-1.5)
<200	0.69 (0.42-1.2)	1.0 (0.69-1.6)
	p_trend=0.53^§	p_trend=0.46^§
HIV viral load
<500	1.0 Referent	1.0 Referent
500-4K	1.1 (0.78-1.6)	0.96 (0.69-1.3)
>4K-20K	1.3(0.97-1.9)	1.1 (0.75-1.5)
>20K	1.1 (0.68-1.9)	1.1 (0.72-1.7)
	p_trend=0.14^§	p_trend=0.73^§
HPV 16 DNA intensity
Negative	1.0 Referent	----
+1	1.3 (0.68-2.4)	----
+2-3	2.2 (1.5-3.2)	----
+4-5	2.4 (1.8-3.1)	----
	p_trend<0.001^§	----
HPV 18 DNA intensity
Negative	----	1.0 Referent
+1	----	1.2 (0.74-1.8)
+2-3	----	1.9 (1.2-3.1)
+4-5	----	2.1 (1.6-2.7)
	----	p <0.001^§
No. of anal receptive partners in last year
None	1.0 Referent	1.0 Referent
1	1.3 (0.88-2.1)	1.3 (0.87-1.9)
2-3	1.5 (0.97-2.2)	1.3 (0.88-2.0)
≥4	1.5 (1.1-2.1)	1.8 (1.3-2.5)
	p_trend=0.012^§	p_trend<0.001^§

^‡

Confidence intervals for relative risks (RR) were computed using robust error variances.

^§

Li kelihood ratio trend test for relative risk.

^¶

Observations with unknown values excluded from analyses.