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Proposed role of components of 1α,25(OH)2D3 membrane-associated receptor complex in Wnt5a calcium-dependent signaling. The effects of Wnt5a are mediated through Pdia3, PLAA and VDR (not shown). Inhibition of CaM, CaMKII, and PLA2 suppressed the activation of PKC in response to Wnt5a treatment.
