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. 2014 Oct 4;15(1):336. doi: 10.1186/1471-2105-15-336

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© Liu et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Illustration of the performance evaluation of SITPR using an example regulatory network. (A) The background regulatory network with 10 nodes. 'G3’ denotes a miRNA and is labeled in magenta. (B) The activated regulatory relationships (edges in color). The numbers next to the edges are the regulatory strengths. (C) An example of the inferred activated regulatory network using SITPR. (D) The ROC curve and the six performance evaluations at the maximum F-measure point.