Fig. 2.
Representative Western blots (A) showing the immunolabeling of GSK-3β and pGSK-3β-ser-9 in the cytosol fraction of dorsolateral prefrontal cortex (DLPFC) of two normal control (NC) subjects, two subjects with schizophrenia (SZ), and two subjects with bipolar disorder (BP). kDa indicates kilo Daltons. Mean protein expression levels of GSK-3β (B) and pGSK-3β-ser-9 (C) in the DLPFC cytosol fractions of NC subjects (n = 20), subjects with BP (n = 19), and subjects with SZ (n = 20) in the in the cingulate gyrus (CG) cytosol fractions of NC (n = 12), BP (n = 12), and SZ (n = 12), and in the temporal cortex (TEMP) cytosol fraction of NC (n = 16), BP (n = 16), and SZ (n = 15). The results are expressed as optical density (O.D.). Values are mean ± standard deviation. *p < 0.05.