Table 1. Baseline characteristics of vivax and falciparum malaria patients and healthy controls.
| P. vivax | P. falciparum | ||||||
| Controls (n = 74*) | Non-severe (n = 53) | Severe (n = 9) | P value (sev vs. ns) | Non-severe (n = 109) | Severe (n = 21) | P value (sev vs. ns) | |
| Age, years | |||||||
| median (IQR) | 35 (23–44) | 24 (18–39) | 39 (30–52) | 0.168 | 25 (17–39) | 33 (19–45) | 0.148 |
| range | 14–69 | 13–61 | 14–79 | 13–78 | 13–60 | ||
| Males, n (%) | 52 (70) | 39 (74) | 9 (100) | 0.105 | 79 (72) | 15 (71) | 0.922 |
| Weight, mean (sd); kg | 58 (10) | 56 (12) | 58 (8) | 0.584 | 56 (13) | 66 (17) | 0.002 |
| Current smoker, n (%) | 30 (41) | 26 (49) | 1 (11) | 0.034 | 37 (34) | 10 (48) | 0.232 |
| Fever duration, days; median (IQR) | 5 (3–7) | 4 (3–4) | 0.135 | 5 (3–7) | 7 (5–7) | 0.014 | |
| Systolic blood pressure, mean (sd); mmHg | 123 (15) | 115 (16) | 119 (18) | 0.451 | 116 (16) | 114 (17) | 0.756 |
| Pulse rate, mean (sd); beats/min | 70 (12) | 87 (19) | 97 (14) | 0.172 | 92 (18) | 98 (16) | 0.123 |
| Respiratory rate, mean (sd); breaths/min | 20 (3) | 24 (5) | 26 (4) | 0.181 | 27 (6) | 31 (7) | 0.006 |
| Temperature, mean (sd); °C | 36.5 (0.4) | 37.4 (1.2) | 36.9 (0.5) | 0.224 | 37.9 (1.1) | 38.1 (1.4) | 0.407 |
| Time from malaria treatment to enrolment, hours; median (IQR) | NA | 5 (0 –– 11) | 10 (6–15) | 0.126 | 5 (0–12) | 4 (0–10) | 0.541 |
*includes all healthy controls who had Near Infrared Spectroscopy and/or blood analysis performed