Table 2. Parasite count and parasite biomass among patients with P. vivax and P. falciparum malaria.
P. vivax | P. falciparum | |||||
Non-severe (n = 53) | Severe (n = 9) | P value (sev vs. ns Pv) | Non-severe (n = 109) | Severe (n = 21) | P value (sev vs. ns Pf) | |
Parasite count (parasites/µL) | 4,209 (1700–10,165) | 10,243 (4387–19,520) | 0.021 | 10,500 (4014–32,267) | 44,332 (9079–273, 909) | 0.002 |
PvLDH (ng/ml) | 26.2 (10.7–57.3) | 96.6 (85.6–154) | 0.012 | |||
PvLDH/Log parasitemia | 3.06 (1.33–7.73) | 10.42 (9.27–18.60) | 0.027 | |||
pLDH (ng/ml) | 44.6 (7.8–142) | 308 (258–619) | 0.015 | 50.23 (22.9–121) | 86.79 (39.3–452) | 0.016 |
pLDH/Log parasitemia | 6.46 (1.60–20.1) | 36.7 (27.9–58.3) | 0.021 | 5.54 (2.33–13.13) | 7.58 (3.51–65.65) | 0.058 |
HRP2 (ng/ml) | 72.8 (32.8–260) | 541 (125–1590) | <0.0001 | |||
HRP2/Log parasitemia | 9.04 (3.38–23.55) | 49.0 (13.8–196) | 0.0002 |
Note: Values are median (inter-quartile range).
Ratios are calculated as ngs/1000 peripheral parasites, with the denominator log-transformed to a normal distribution.