Table 1. Transmission pair information.

Patient IDa	Statusb	Virus subtype	Fiebig stagec	pVLd copies/ml	HLA class I alleles
R880M	D	A1	NA	13,929	A*0109	A*3303	B*4415	B*5703	Cw*0407	Cw*1701
R880F	LR	A1	III	430,843	A*0201	A*0301	B*1503	B*4701	Cw*0210	Cw*0602
R463M	D	A1	NA	108,624	A*0101	A*2301	B*4415	B*8101	Cw*0407	Cw*1801
R463F	LR	A1	IV	152,000,000	A*0101	A*3002	B*1503	B*4501	Cw*0210	Cw*0602

^aM: male; F: female.

^bD: donor, LR: virologically linked recipient.

^cFiebig stage: Fiebig stage of the recipients at the time of enrollment into the IAVI protocol C early infection study, when plasma was first collected for viral sequence analysis.

^dpVL: Plasma viral loads for the recipients are shown at the time of screening prior to enrollment into the IAVI protocol C early infection study, when R880F was at Fiebig stage III and R463F at Fiebig stage IV. The plasma viral load in R463F at Fiebig stage V was 3,980,000 copies/ml. Plasma viral loads in the donors are shown at the timepoint when the recipients were at Fiebig stage III/IV.