Table 3. Diagnostic performance of microscopy and Pan-mLAMP kit for active case detection (ACD) of asymptomatic infections and compared to 3-well nested RT-PCR as reference standard (n = 980).

Method and Parasite species	Parameter	%	95% CI
Microscopy	Sensitivity	0	0 to 6.5
P. vivax	Specificity	100	99.6 to 100
	PPV	—
	NPV	9.4	92.80 to 95.7
Microscopy	Sensitivity	5.9	0.2 to 28.7
P. falciparum	Specificity	99.9	99.4 to 100
	PPV	50.0	0.04 to 99.9
	NPV	98.4	97.36 to 99.0
Pan-mLAMP	Sensitivity	90.9	80.0 to 97.0
P. vivax	Specificity	99.5	98.7 to 99.8
	PPV	90.9	79.9 to 97.0
	NPV	99.5	98.7 to 99.8
Pan-mLAMP	Sensitivity	100	78.2 to 100
	Specificity	99.9	99.4 to 100
P. falciparum	PPV	93.8	69.8 to 99.8
	NPV	100	99.6 to 100