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. 2015 Jan 8;11(1):e1004579. doi: 10.1371/journal.ppat.1004579

Figure 6. Monocytes and neutrophils are the main cellular targets of hResistin during Nb infection.

Figure 6

(A-B) Lung cells from Nb-infected mice were incubated with recombinant hResistin followed by detection with α-hRetn to determine which cells can bind hResistin compared with control PBS (A). Surface expression of the hResistin-bound cells identified monocytes as the main cell-type that bound hResistin (B). (C) Sorted lung cells from Nb-infected hRetnTg− and hRetnTg+ mice were analyzed for proinflammatory gene expression by real-time PCR. Data (mean ± SEM, n = 3–4 per group) are representative of two separate experiments.