Metyrapone (MTP) blocks the effects of maternal food restriction (MFR) on key pulmonary lipogenic and myogenic differentiation markers. At postnatal day 21 (p21), in both males and females, MTP normalized the MFR-induced decrease in peroxisome proliferator-activated receptor γ (PPARγ; A) and MFR-induced increase in fibronectin (B), α smooth muscle actin (α-SMA; C), calponin (D), GR (E), and β-catenin (F) protein levels, as determined by Western blotting. * = P < .05 FA versus AA and # = P < .05 FA + M versus FA; N = 6. AA indicates ad libitum diet; FA+ M, food-restricted diet with MTP.