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Metyrapone (MTP) blocks the effect of maternal food restriction (MFR)-induced increase in pulmonary myogenic proteins and Wnt signaling intermediates. Immunohistochemistry of postnatal day 21 (p21) lungs shows that MFR-induced increase in protein levels of α smooth muscle actin (a-SMA; A), calponin (B), β-catenin (C), and lymphoid enhancer-binding factor 1 (LEF-1; D) is blocked by MTP.
