Table 7.
Pharmacokinetic properties of OSU-T315
PK parameters | Intravenous (50 mg/kg) | Orally (50 mg/kg) | Intraperitoneally (25 mg/kg) |
---|---|---|---|
Cmax (nM) | 48 764 | 369.09 | 3604 |
Tmax (minutes) | 5 | 120 | 120 |
T1/2 (hours) | 5.51 | 5.07 | 6.08 |
Bioavailability (%) | NA | 5.8 | 58.6 |
NA, not applicable.