Table 3.
Risk of type 2 diabetes by quartiles of the lipophilic index in a case-cohort study embedded in the EPIC-Potsdam cohort (n = 1,740)
| Quartile of lipophilic index | |||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | p value | |
| Median index | 21.5 | 23.2 | 24.7 | 26.8 | |
| n (cases/ subcohort) | 68/351 | 70/352 | 88/351 | 136/352 | |
| Model 1a | 1.00 (ref.) |
0.97 (0.67, 1.40) |
1.28 (0.89, 1.84) |
1.76 (1.25, 2.47) |
<0.001 |
| Model 2b | 1.00 (ref.) |
0.97 (0.65, 1.43) |
1.36 (0.93, 1.99) |
1.85 (1.29, 2.65) |
<0.001 |
| Model 3c | 1.00 (ref.) |
0.94 (0.61, 1.43) |
1.18 (0.78, 1.78) |
1.59 (1.08, 2.34) |
0.005 |
| Model 3 + diabetes-related FAsd | 1.00 (ref.) |
0.96 (0.62, 1.49) |
1.36 (0.88, 2.08) |
1.90 (1.25, 2.90) |
<0.001 |
Data are HRs (95% CI)
aModel 1 is stratified by age and adjusted for sex
bModel 2 is further adjusted for sports activity, biking, smoking status, education, alcohol consumption, total energy intake, coffee intake, sugar-sweetened beverage intake, dietary PUFA/SFA ratio and intake of protein and carbohydrates (energy-adjusted)
cModel 3 is further adjusted for BMI and waist circumference
dDiabetes-related FAs: 15:0, 17:0, 18:0, 16:1 n-7, 18:2 n-6, 18:3 n-6, and 20:3 n-6