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. 2015 Jan 9;5:7613. doi: 10.1038/srep07613

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Transit time (a) and cell volume (b) measured from 5 control/healthy samples (red) and 5 CLL samples (cyan). For each sample, the three lines of the box represent 75 percentile, median, and 25 percentile; the whiskers represent the locations of maximum and minimum (n ≈ 1,000 for each sample). The average median values of transit time (c) and cell diameter (d) of the 5 control samples and the 5 CLL samples are 3.5 ± 0.16 ms vs. 5.1 ± 0.44 ms and 7.3 ± 0.03 μm vs. 7.1 ± 0.06 μm, respectively. In general, cells in CLL samples are slightly smaller than cells in control samples but reveal a longer transit time, indicating that they are less deformable. (e) and (f) summarize the difference of 75 and 25 percentile of cell transit time and diameter. *p was calculated using Mann-Whitney nonparametric analysis; and error bars represent standard error of the mean value.