Figure 4.
(a) Experimental AFM indentation curves of two representative lymphocytes, one from control sample and one from CLL sample. The elastic moduli of lymphocytes were quantitatively determined by fitting force-indentation curves to standard Hertz model for a pyramidal tip. (b) Elastic modulus values of the control sample (n = 10) and the CLL sample (n = 14). *p was calculated using Mann-Whitney nonparametric analysis.
