Figure 6. PAM did not exhibit retinal toxicity.
(A) Color fundus image and (B) H&E staining of a cryosection of wild-type mouse eyes injected with PAM showing no retinal degeneration. (C) Representative electroretinogram from an eye injected with PAM. (D, E) Neither ERG a-waves (D) nor b-waves (E) showed significant differences between eyes injected with PAM and control (Crtl) eyes. Scale bar (B) = 50 μm. N.S. = not significant.