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. 2014 Aug 1;592(Pt 20):4507–4521. doi: 10.1113/jphysiol.2014.277616

Figure 6. Cyclic stretch activation of EGFR and p44/42 MAPK is dependent on ADAM17 activity.

Figure 6

Western blots demonstrate activation of EGFR (A) and p44/42 MAPK (B) is blocked by TAPI-1. *P < 0.001 vs. static; †P < 0.05 vs. stretch+vehicle (dimethyl sulfoxide); n = 8. EGFR, epidermal growth factor receptor; MAPK, mitogen-activated protein kinase.