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. 2015 Jan 9;5:7691. doi: 10.1038/srep07691

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Lymph node CD44^hiCD62L^hi (effector) and CD44^hiCD62L^lo (memory) CD4⁺ T cells from 4-month-old B6/lpr, B6/lpr-p21tg, B6 and B6-p21tg mice were analyzed by flow cytometry. (a) Reduced CD69 expression in B6/lpr-p21tg CD44^hiCD62L^hi CD4⁺ T cells compared with those from B6/lpr mice. Data are from one representative experiment (n = 4 mice; p < 10⁻⁴) of 2 performed. CD69 levels were similar on B6-p21tg and B6 CD44^hiCD62L^hi CD4⁺ T cells. (b) Similar CD69 expression for B6/lpr-p21tg and B6/lpr CD44^hiCD62L^lo CD4⁺ T cells and the equivalent B6-p21tg and B6 cell populations. Data from one representative experiment of two performed (n = 4 mice each).