Table 3.
Genotype and allele frequencies of G894T eNOS polymorphism in patients with ischemic stroke and controls.
| Genotypes/alleles | Cases (%) N = 165 |
Control (%) N = 182 |
OR (95% CI) | P value |
|---|---|---|---|---|
| GG | 83 (50.3) | 117 (64.3) | 1 | |
| GT | 66 (40.0) | 58 (31.9) | 1.60 (1.02–2.52) | 0.040a |
| TT | 16 (8.0) | 7 (3.8) | 3.22 (1.27–8.18) | 0.014a |
| GG + GTb | 149 (90.3) | 175 (96.2) | 1 | |
| TT | 16 (9.7) | 7 (3.8) | 2.68 (1.08–6.70) | 0.034a |
| GGc | 83 (50.3) | 117 (64.3) | 1 | |
| GT + TT | 82 (46.7) | 65 (35.7) | 1.78 (1.16–2.73) | 0.009a |
| Gd | 232 (70.3) | 292 (80.2) | 1 | |
| T | 98 (29.7) | 72 (19.8) | 1.71 (1.21–2.43) | 0.003a |
N: Number, OR: odds ratio, CI: confidence interval, P < 0.05, vs.: versus, Ref.: reference, %: percentage.
a
Significant.
b
TT vs. GG + GT (recessive model) for G894T eNOS.
c
GT + TT vs. GG (dominant model) for G894T eNOS.
d
T vs. G (additive model) for G894T eNOS.