Table 2.
Genotype & allele frequencies of FABP2 & PPARG2 genes in cataract cases and healthy controls. Bold values indicate p value is less than 0.05.
| FABP2 |
||||||
|---|---|---|---|---|---|---|
| Group | Alleles & genotype | AA | AT | TT | A | T |
| Control (118) | N (%) | 30 (25.42%) | 73 (61.86%) | 15 (12.71%) | 133 (56.35%) | 103 (43.64%) |
| Cataract cases (130) | N (%) | 66 (50.76%) | 51 (39.23%) | 13 (10%) | 183 (70.38%) | 77 (29.61%) |
| OR/95% CI | 3.03/(1.76–5.18) | 0.40/(0.24–0.66) | 0.76/(0.35–1.68) | 1.84/(1.27–2.67) | 0.54/(0.38–0.79) | |
| p-Value/chi sq | < 0.0001/16.75 | 0.0004/12.67 | 0.500/0.45 | 0.001/10.53 | 0.001/10.53 | |
| Power | 0.97 | 0.923 | 0.549 | 0.922 | 0.922 | |
| PPARG2 |
||||||
| Group | Alleles & genotype | CC | CG | GG | C | G |
| Control (118) | N (%) | 25 (21.18%) | 47 (39.83%) | 46 (38.98%) | 97 (41.10%) | 139 (58.89%) |
| Cataract cases (130) | N (%) | 15 (11.53%) | 114 (87.69%) | 1 (0.76%) | 144 (55.38%) | 116 (44.61%) |
| OR/95% CI | 0.49/(0.24–0.97) | 10.76/(5.68–20.41) | 0.01/(0.002–0.090) | 1.79/(1.25–2.54) | 0.56/(0.39–0.80) | |
| p-Value/chi sq | 0.039/4.26 | < 0.0001/62.22 | < 0.0001/58.81 | 0.001/10.10 | 0.001/10.10 | |
| Power | 0.765 | 0.999 | 0.999 | 0.919 | 0.919 | |