Fig. 1.

Median joining network of PSMA6/PSMC6/PSMA3 haplotypes. The network was generated using the Reduced Median algorithm of the Phylogenetic network software Fluxus 4.611 (http://www.fluxus-engineering.com). Panel A: LV — Latvians, LT — Lithuanians, CEU — NorthWestern Europeans; Panel B: TW — Taiwanese, HCB — Han Chinese, JPT — Japanese. Haplotypes are numbered as in Table 3. Mutations at the rs2277460, rs1048990, rs2295826&rs2295827 and rs2348071 are indicated as stars of interrupted outline, grey, black and white colours respectively. Length of the branches is equal to time of generation and dissemination of progeny haplotype.