Table 3.
Haplotype |
Populations (2n) |
||||||
---|---|---|---|---|---|---|---|
ID | 1–2–3–4–5 | LV (382) | LT (300) | CEU (94) | TW (2194) | HCB (80) | JPT (86) |
Hap 1 | CCACG | 0.5576 | 0.4967 | 0.6064 | 0.2388 | 0.1875 | 0.2558 |
Hap 2 | CCACA | 0.2068 | 0.1467 | 0.2021 | 0.3464 | 0.3000 | 0.2209 |
Hap 3 | CCGTG | 0.0681 | 0.0833 | 0.0638 | 0.0264 | ||
Hap 4 | ACACA | 0.0393 | 0.0267 | 0.0106 | 0.0027 | ||
Hap 5 | CGACA | 0.0340 | 0.0067 | 0.0745 | 0.1796 | 0.2625 | 0.2791 |
Hap 6 | CGACG | 0.0314 | 0.1100 | 0.0426 | 0.0706 | 0.0625 | 0.0581 |
Hap 7 | ACACG | 0.0262 | 0.0400 | 0.0046 | |||
Hap 8 | CGGTG | 0.0236 | 0.0625 | 0.0116 | |||
Hap 9 | CCGTA | 0.0131 | 0.0300 | 0.0510 | 0.1250 | 0.1163 | |
Hap 10 | CGGTA | 0.0333 | 0.0643 | 0.0581 | |||
Hap 11 | ACGTA | 0.0233 | |||||
Hap 12 | AGACG | 0.0033 | |||||
Hap 13 | CGGCA | 0.0068 | |||||
Hap 14 | CCGCG | 0.0023 | |||||
Hap 15 | CGGTG | 0.0023 | |||||
Hap 16 | CGATA | 0.0018 | |||||
Hap 17 | CCGCA | 0.0014 | |||||
Hap 18 | CCATG | 0.0009 | |||||
Hd | 0.638 | 0.710 | 0.586 | 0.779 | 0.792 | 0.797 | |
Test of neutrality | |||||||
Tajima's D, DT | 0.71472 | 1.35443 | − 0.20222 | 2.00713nd | 1.85362#* | 1.91830#* | |
Fu and Li's D* | 0.93163 | 0.94926 | − 0.01266 | 0.82277 | 0.96034 | 0.95389 | |
Fu and Li's F* | 1.02654 | 1.29964 | − 0.08777 | 1.52548#* | 1.45955 | 1.1.48121#* | |
LD 3–4 | |||||||
D´ | 1.000 | 1.000 | 1.000 | 0.978 | 1.000 | 1.000 | |
r2 | 1.000***B | 1.000***B | 1.000***B | 0.901***B | 1.000***B | 1.000***B |
The loci 1, 2, 3, 4, and 5 in haplotypes' configurations correspond in sequence to the rs2277460, rs1048990, rs2295826, rs2295827 and rs2348071 loci respectively; Hd — haplotype diversity; LD — linkage disequilibrium. Statistical significance levels of probability correspond to: #* 0.10 > P > 0.05; nd not determined: P = 0.05; *** P < 0.001; B — Bonferroni correction for multiple tests.