Table 3.
5-Hydroxyindoleacetic Acid (5-HIAA) comparisons by diagnosis, adjusting for post-conceptional age (PCA) and postmortem interval (PMI)
| 5-HIAA | ||
|---|---|---|
| Adjusted Mean (Standard Error) in nmol/L | P-value of Pair-wise Comparisons between Groups of Interest | |
| SIDS cases, n=52 | 1191.8 (67.6) | SIDS vs. AC (0.839) SIDS vs. CC (0.915) SIDS vs. AA (0.999) SIDS vs. RSIDS (1.000) SIDS vs. UND (0.526) AC vs. CC (0.999) AC vs. AA (0.861) |
| Acute Controls (AC), n=9 | 1399.9 (161.0) | |
| Chronic Controls (CC), n=2 | 1546.8 (347.8) | |
| Acute Asphyxia (AA), n=8 | 1126.7 (175.1) | |
| Resuscitated SIDS (RSIDS), n=5 | 1150.3 (220.5) | |
| Undetermined cases(UND), n=10 | 904.7 (152.6) | |
Legend: A Tukey-Kramer adjustment was used to account for the multiple comparisons. The p-values are presented in the brackets. There was no difference in 5-HIAA levels between the SIDS and non-SIDS (AC, CC, and AA groups combined) (p-value=0.824). Abbreviation: vs., versus.