Table 4.
Homovanillic Acid (HVA) comparisons by diagnosis, adjusting for post-conceptional age (PCA) and postmortem interval (PMI)
HVA | ||
---|---|---|
Adjusted Mean (Standard Error) in pmol/L | P-value of Pair-wise Comparisons between Groups of Interest | |
SIDS cases, n=52 | 1557.7 (177.4) | SIDS vs. AC (0.004) SIDS vs. CC (0.963) SIDS vs. AA (0.989) SIDS vs. RSIDS (0.485) SIDS vs. UND (0.729) AC vs. CC (0.923) AC vs. AA (0.019) |
Acute Controls (AC), n=9 | 3305.2 (423.0) | |
Chronic Controls (CC), n=2 | 2321.9 (915.6) | |
Acute Asphyxia (AA), n=8 | 1245.9 (462.4) | |
Resuscitated SIDS (RSIDS), n=5 | 2755.1 (645.3) | |
Undetermined cases(UND), n=10 | 914.2 (424.0) |
Legend: A Tukey-Kramer adjustment was used to account for the multiple comparisons. The p-values are presented in the brackets. There was no difference in HVA levels between the SIDS and non-SIDS (AC, CC, and AA groups combined) (p-value=0.130). Abbreviation: vs., versus.