Figure 6. CA sheets roll to form cores.

(a) A slice through a tomogram showing the CA layer detaching from the membrane of a multi-core membrane-enclosed structure and wrapping around the interior of the core. (b) A 3D rendering of the core in a. (c) A slice through a tomogram of a core at a late stage of formation. The core is fully formed but still attached to the membrane. (d) 3D rendering of the core in c. (e) A slice through a tomogram, showing a section perpendicular to the long axis of a forming core inside a regular size virion. A sheet of CA is connected to the virion envelope on one side and is curling around the core towards the centre of the virion. (f) A 3D rendering of the core in e. All scale bars, 50 nm.