Table 2.
Evidence degree assignment criteria for clinicogenomic associations.
| Order of preference | Value | |
| Credibility of referenced article |
|
|
|
|
Citation number of article | (1-15)=1, (16-50)=2, and (>50)=3 |
|
|
Type of study and number of authors | (Research article and author number <10) =1; (research article and ≤10 author number <35)=2; (research article and ≤35 author number)=3; (meta-analysis and author number<7) =2; and (meta-analysis and ≥7 author number)=3 |
| Reliability of study |
|
|
|
|
Race and ethnicity of studies population | Other races (Africans, Asians, etc)=1; mixed=2; and Caucasians=3 |
|
|
Sample size (each of case and controls) | (<100)=1; (≥100 and <1000)=2; and (>1000)=3 |
| Scientific familiarity of SNP-disease relationship |
|
|
|
|
Number of article for SNP-prostate cancer relationship in PubMed | (<7)=1; (≥7 and <19)=2; and (≥20)=3 |
|
|
Number of cumulative models which involve SNP allele | None=1, (<3)=2, and (≥3) =3 |
| Degree of evidence quality |
|
|
|
|
=Total value/6 (<1.5)= weak; (≤1.5 and <2.3)= moderate; and (≤2.3)= strong |
|