Table 1.

List of expected manifestations (differences between DTA and treatment reviews) for all hypotheses.

Manifestation	Description	Hypothesis A: Increased Workload	Hypothesis B: Increased Target Class Heterogeneity	Hypothesis C: Decreased Suitability of Metadata
FTa	The mean number of full-text articles screened would be higher for DTA reviews than for treatment	Yes	-	-
SRb	The mean number of search results would be higher for DTA reviews than for treatment	Yes	-	Yes
INCc/ FT	The number of included studies as a percentage of the number of full-text articles screened would be lower for DTA reviews than for treatment	-	Yes	-
INC/SR	The number of included studies as a percentage of the total number of search results would be lower for DTA reviews than for treatment	Yes	-	-
FT/SR	The number of full-text articles retrieved as a percentage of the total search results would be lower for DTA reviews than for treatment	-	-	Yes

^anumber of references for which full-text papers were screened

^bnumber of references retrieved by the original search

^cnumber of references included in the final meta-analysis