Table 2.
Correlation of PD-L1 expression and clinico-pathological factors in non-ccRCC
| Characteristic | % Positive tumor cell membrane |
P value | TIMC |
P value | ||||
|---|---|---|---|---|---|---|---|---|
| <5% (negative) (N = 90, 89.1%), n (%) | 5% or more (positive) (N = 11, 10.9%), n (%) | Total (N = 101) | Score = 0 (negative) (N = 44, 43.6%), n (%) | Score >0 (positive) (N = 57, 56.4%), n (%) | Total (N = 101) | |||
| Stage | ||||||||
| 1 | 52 (58) | 2 (20) | 54 (53) | 0.01 | 24 (55) | 30 (54) | 54 (53) | 0.35 |
| 2 | 18 (20) | 1 (10) | 19 (19) | 11 (25) | 8 (14) | 19 (19) | ||
| 3 | 14 (16) | 4 (40) | 18 (18) | 7 (16) | 11 (20) | 18 (18) | ||
| 4 | 6 (7) | 3 (30) | 9 (9) | 2 (5) | 7 (12) | 9 (9) | ||
| Unknown | 0 | 1 (1) | 1 (1) | 0 | 1 (1) | 1 (1) | ||
| Fuhrman grade | ||||||||
| I/II | 51 (57) | 2 (18) | 53 (52.4) | 0.03 | 23 (53) | 30 (53) | 53 (52.4) | 0.11 |
| III | 31 (35) | 7 (64) | 38 (37.6) | 19 (44) | 19 (33) | 38 (37.6) | ||
| IV | 7 (8) | 2 (18) | 9 (9) | 1 (1) | 8 (14) | 9 (9) | ||
| Unknown | 1 (1) | 0 | 1 (1) | 1 (1) | 0 | 1 (1) | ||
| Histology | ||||||||
| Chromophobe | 34 (94.4) | 2 (5.6) | 36 (36) | 0.1 | 23 (63.9) | 13 (36.1) | 36 (36) | 0.001 |
| Collecting duct | 4 (80) | 1 (20) | 5 (5) | 0 (0) | 5 (100) | 5 (5) | ||
| Papillary | 45 (90) | 5 (10) | 50 (49) | 20 (40) | 30 (60) | 50 (49) | ||
| Translocation | 7 (70) | 3 (30) | 10 (10) | 1 (10) | 9 (90) | 10 (10) | ||
TIMC, tumor-infiltrating mononuclear cells.