Table 2. Overview of the fitted model parameters and comparison to values reported in the literature.

Process	Activation	Deactivation	Reversion	Initiation	Elongation	Splicing	Maturation	Degradation
Value of fitted rate constant, min−1	0.106	1.3	1.145	3.436	2.272 0.45 kb/minb	0.512	0.161	0.025
Dependent confidence interval	0.0022	0.0256	0.2840	0.0627	0.4780	0.0158	0.0337	0.0008
Independent confidence interval	0.0499	6.8337	4.9264	18.9385	0.7861	0.0817	0.0940	0.0047
Characteristic time, mina	47.1	3.8	4	0.27	2.2	9.8	31.1	202.4
Reported range for characteristic time	10–150 min (38)	1–15 min (38)	N/A	0.8 min (41)	0.38 -3 kb/min (40,41)	5–10 min (40)	–	30–900 min (∼300c min) (25,46)

^aThe characteristic times are defined as n/k, with n as the number of elementary steps in the processes (always n = 5 except for initiation where n = 1).

^bThe elongation rate in kb/min as calculated from the fitted characteristic time (2.2 min) and the length of the amplified fragment (1178 nt).

^cDegradation rate found specifically for ADRP mRNA.