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. 2014 Dec 8;43(1):461–469. doi: 10.1093/nar/gku1296

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© The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — (A) Fraction of substrate cleavage by the Tm7 DNAzyme using 10 or 100 μM metal ions. Inset: gel image of cleavage in the presence of 10 μM metal ions. The lanes correspond to the metal ions in the x-axis. Only Au³⁺ produced streaking and Er³⁺ and Y³⁺ produced cleavage. (B) Kinetics of Tm7 cleavage at a few Er³⁺ concentrations. (C) Cleavage rate as a function of Er³⁺ concentration. Inset: the same data plotted using the log scale.