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(A) Overview of the specific nOe contacts of the Hϵ1 proton of T8Im, T8ImA21, sT21Im and T7ImH to the DNA backbone (2D NOESY, 200 ms, 700 MHz, 25°C, D2O). (B) Schematic overview of the specific nOe-contacts from the T8ImH+ Hϵ1 (□) and Hδ2 (◊) protons to the nucleotides up-stream from the modification site.
