Table 4. Cox regression analyses for cancer-specific survival after surgery in cohort 3 (46 CRPC patients).

Covariates	Univariate analysis		Multivariate analysis
	HR (95% CI)	p Value	HR (95% CI)	p Value
Age at diagnosis (ref: <65 years)	0.973 (0.941–1.007)	0.122	0.977 (0.943–1.012)	0.189
PSA at diagnosis (ref: 98 ng/mL)	1.000 (0.999–1.000)	0.473	1.000 (0.999–1.001)	0.841
Gleason score at diagnosis (ref: ≤7)	0.820 (0.445–1.510)	0.524	0.870 (0.441–1.714)	0.687
M stage at diagnosis (ref: M0)
M1	1.668 (0.768–3.622)	0.196	1.129 (0.463–2.754)	0.790
Time to CRPC (ref: <24 months)	0.492 (0.264–0.917)	0.025	0.397 (0.199–0.793)	0.009
PSADT (ref: <1.7 months)	0.478 (0.259–0.882)	0.018	0.590 (0.299–1.164)	0.128
Age at TURP (ref: <70 years)	0.972 (0.940–1.005)	0.094	1.449 (0.598–3.512)	0.411
PSA at TURP (ref: <61.3 ng.mL)	0.999 (0.998–1.001)	0.344	0.999 (0.998–1.000)	0.207
M stage at TURP (ref: M1b)
M1c	2.295 (1.081–4.876)	0.031	0.974 (0.939–1.009)	0.142
AR-V7 expression (ref: negative)	2.646 (1.348–5.193)	0.005	2.247 (1.066–4.737)	0.033