Table IV. Sensitivity and specificity of epitope candidates.
Sequence | Infection | Sensitivity | Specificity |
---|---|---|---|
AVHAD | Dengue | 1 | 1 |
REGEK | Dengue | N/A | N/A |
DYAFG | Syphilis | 1 | 1 |
EDAK | Lyme disease | 0.125 | 1 |
FKEG | Pertussis | 0.83 | 1 |
SNKQG, RLKEP | Malaria | 0.69 | 1 |
DAFEY | Malaria | 0.46 | 1 |
Sensitivity and specificity calculations for the top epitope candidates from Table III. The selection algorithm maximizes sensitivity and might not be a reliable estimate of performance. However, the candidates do map to antigenic proteins and are specific to the cohort of interest. Estimates for the REGEK sequence from dengue could not be computed, as this was discovered using a separate set of arrays or too few samples were processed.