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Model for the origin of SMMs. SMM networks contain relocated host proteins from endocytic and intracellular host trafficking routes, as well as components of mitochondrial, ribosomal, ER, and nuclear origin identified in this study. Proteins known to be involved in SIF or SCV formation are italicized or bolded, respectively. Mt, microtubule; Mtch, mitochondrium; VAP, vacuole-associated actin polymerization; S.Tm, Salmonella Typhimurium.
