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. 2014 Nov 26;19(1):21–30. doi: 10.1111/jcmm.12425

Table 2.

Selected ADSC secretomes and their functions

Growth factor Function Source articles
Brain-derived growth factor (BDNF) Nerve regeneration Salgado et al., 2010; Lopatina et al. 2011; Reid et al., 2011; Sowa et al., 2012; Kingham et al., 2013
Glial-derived growth factor (GDNF) Nerve regeneration Salgado et al., 2010; Reid et al., 2011; Lopatina et al. 2011; Kingham et al., 2013
Hepatocyte growth factor (HGF) Angiogenesis, wound healing, immunomodulation Wang et al., 2006; Kapur et al., 2013
Insulin-like growth factor-1 (IGF-1) Wound healing, nerve regeneration, cardiac regeneration Wang et al., 2006; Salgado et al., 2010; Kapur et al., 2013
Nerve growth factor (NGF) Nerve regeneration Salgado et al., 2010; Reid et al., 2011; Lopatina et al. 2011; Sowa et al., 2012
Vascular endothelial growth factor (VEGF) Angiogenesis, wound healing, cardiac regeneration, immunomodulation Wang et al., 2006; Sowa et al., 2012; Kingham et al., 2013; Kapur et al.,2013
Transforming Growth Factor beta (TGF-β) Angiogenesis, immunomodulation Salgado et al., 2010; Lopatina et al. 2011; Kapur et al., 2013
Basic Fibroblast Growth Factor (bFGF) Angiogenesis Salgado et al., 2010; Kapur et al., 2013
Granulocyte colony-stimulating factor (G-CSF) Angiogenesis, wound healing Wound healing Kapur et al., 2013
Interleukin 6 (IL-6) Immunomodulation Kapur et al., 2013
Interleukin 8 (IL-8) Wound healing Kapur et al., 2013

ADSC, Adipose-derived stem cell.