Skip to main content
. 2014 Aug 25;17(2):243–253. doi: 10.1093/neuonc/nou217

Fig. 6.

Fig. 6.

Overexpression of miR-326 inhibited tumor growth in vivo and prolonged survival. (A) Luminescence imaging for miR-326–treated U251-luc tumors versus scramble-treated controls. (B) H&E-stained coronal brain sections showing representative tumor xenografts. (C) miR-326 and SMO expression in an intracranial graft assessed by RT-PCR and Western blot. (D) SMO and GLI1 expression after transfecting miR-326 in tumor sections following IHC analysis (*P < .05; the bars represent 25 μm). (E) Kaplan-Meier survival curves indicating that mice transfected with miR-326 showed a significantly better outcome than the miR-Scr-treated group (*P < .05).